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Title Author Journal Technique(s) Model Organism Research Area Product
The role of TGF-beta in Ebola virus infection of human hepatocytes as assessed by phenotypic screening Jason Kindrachuk, Victoria Wahl-Jensen, David Safronetz, Brett Trost, Thomas Hoenen, Ryan Arsenault, Friederike Feldmann, Dawn Traynor, Elena Postnikova, Anthony Kusalik, Scott Napper, Joseph E. Blaney, Heinz Feldmann and Peter B. Jahrling Journal of Virology, 88 (17): 9877-9892. September 2014. Infectious Diseases Harmony
Operetta
Analysis of macrophage morphology changes following R. equi infection Miranda-CasoLuengo AA, Miranda-CasoLuengo R, Lieggi NT, Luo H, Simpson JC and Meijer WG PLoS ONE 8(3): e60612. doi:10.1371/journal.pone.0060612 Mar 2013 Infectious Diseases
Microbiology
Columbus
Studying Eu-labeled alpha-gal A uptake in pathologically relevant cell models of Fabry disease Marchesan D, Cox TM and Deegan PB Journal of Inherited Metabolic Diseases; 35: 1107–1117 Nov 2012 Metabolic Disorders VICTOR
DELFIA
Quantification of prostate cancer biomarkers using multiplexed IHC on prostate TMAs Huang W, Hennrick K and Drew S. Human Pathology 44 (1): 29-38. Jan 2013 Image Segmentation
Quantitative measurements
Cancer Biology Vectra
inForm
Nuance
Quantitative Visualization of DNA G-Quadruplex Structures in Human Cells Biffi G, Tannahill D, McCafferty J & Balasubramanian S Nature Chemistry 5 (3): 182-186. Jan 2013 Colocalization
Quantitative measurements
Cancer Biology
Cell Cycle
Genetics
Volocity
A novel chemical biology strategy to study epigenetic regulation using phenotypic screening Liu Y, Platchek M, Kement B, Bee WT, Truong M, Zeng X, Hung S, Lin H, Morrow D, Kallal LA, Xie Q, Agarwal P, Pope AJ and Wu Z Molecular BioSystems, 2014, Advance Article Drug Discovery
Epigenetics
Acapella
Opera
TIBCO Spotfire
Image-based quantitative analysis of C4d deposits in rat kidney transplants Seifert M, Stolk M, Polenz D and Volk H-D Frontiers in Immunology 2012 3: 202 doi: 10.3389/fimmu.2012.00202 Quantitative measurements Immunology Columbus
Development of a homogeneous AlphaLISA ubiquitination assay using ubiquitin binding matrices as universal components for the detection of ubiquitinated proteins Schneider S, Chen H, Tang J, Emkey R and Andrews PS Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823 (11): 2038-2045. Apr 2012 AlphaLISA Technology
Quantification of LC3B protein levels in autophagic particles using Volocity software Colecchia D, Strambi A, Sanzone S, Lavarone C, Rossi M, Dall’Armi C, Piccioni F, Verrotti di Pianella A and Chiariello M Autophagy 8 (12): 1-17. Dec 2012 Quantitative measurements Cell Signalling Volocity
Synergistic combinations of lipidoids for efficacious siRNA delivery Whitehead KA, Sahay G, Li GZ, Love KT, Alabi CA, Ma M, Zurenko C, Querbes W, Langer RS and Anderson DG Molecular Therapy, 19 (9): 1688-1694. Sep 2011 Quantitative measurements
RNAi
Mouse Method Development
RNAi Screening
Acapella
Opera
IVIS
Quantification of siRNA levels using the Columbus Image Data Storage and Analysis System Bin Shi, Ed Keough, Andrea Matter, Karen Leander, Stephanie Young, Ed Carlini, Alan B. Sachs, Weikang Tao, Marc Abrams, Bonnie Howell and Laura Sepp-Lorenzino Journal of Histochemistry & Cytochemistry 59 (8): 727-740 Aug 2011 Quantitative measurements
RNAi
Method Development
Molecular Biology
RNAi Screening
Columbus
Opera
Validation of a Novel Four-Marker Signature for Prostate Cancer Progression Using Trainable Pattern Recognition and Multispectral Imaging Ding Z, Wu C-J, Chu GC, Xiao Y, Ho D, Zhang J, Perry SR, Labrot ES, Wu X, Lis R, Hoshida Y, Hiller D, Hu B, Jiang S, Zheng H, Stegh AH, Scott KL, Signoretti S, Bardeesy N, Wang YA, Hill DE, Golub TR, Stampfer MJ, Wong WH, Loda M, Mucci L, Chin L, DePinho Nature 470 (7333): 269–273. Feb 2011 Cancer Biology Vectra
inForm
Quantification of lipid droplets using Volocity software David A. Gross, Chenyang Zhan and David L. Silver PNAS, 108 (49): 19581-19586 Dec 2011 Quantitative measurements
Visualization
Obesity
Organelle Biology
Protein Biochemistry
Volocity
Live Cell Imaging of Rab5 Localization During Mitosis Gaetana Serio, Valentina Margaria, Sanne Jensen, Amanda Oldani, Jiri Bartek, Federico Bussolino and Letizia Lanzetti PNAS; 108 (42) 17337-17342 Oct 2011 Acquisition Cancer Biology
Cell Cycle
Volocity
UltraVIEW
High Content Screening Analysis of Phospholipidosis Van de Water FM, Havinga J, Ravesloot WT, Horbach GJ and Schoonen WG Toxicology In Vitro; 25 (8): 1870-1882. Dec 2011 Quantitative measurements Drug Discovery
Method Development
Harmony
Operetta
Imaging the dynamics and epigenetic control of inactive X chromosome replication Casas-Delucchi CS, Brero A, Rahn H-P, Solovei I, Wutz A, Cremer T, Leonhardt H and Cardoso MC Nature Communications; 2 (222). doi:10.1038/ncomms1218 Mar 2011 Mouse Cell Cycle
Epigenetics
UltraVIEW
In vivo imaging: a powerful tool for tumor neovascularization studies Hanyu A, Kojima K, Hatake K, Nomura K, Murayama H, Ishikawa Y, Miyata S, Ushijima M, Matsuura M, Ogata E, Miyazawa K and Imamura T Cancer Science; 100 (11): 2085-2092 Nov 2009 Mouse Cancer Biology AngioSense
Development and Validation of a High Content Screening In Vitro Micronucleus Assay Westerink WM, Schirris TJ, Horbach GJ and Schoonen WG Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 724 (1-2): 7-21 Sep 2011 Drug Discovery
Toxicology
Acapella
Harmony
Operetta
Investigating Alzheimer’s Disease Pathology using Operetta Rammes G, Hasenjäger A, Sroka-Saidi K, Deussing JM and Parsons CG Neuropharmacology; 60 (6): 982-990 Jan 2011 Neuroscience
Pharmacology
Harmony
Operetta
Imaging zebrafish neutrophils and macrophages during inflammation Gray C, Loynes CA, Whyte MKB, Crossman DC, Renshaw SA and Chico TJA Thrombosis and Haemostasis; 105 (4) jan 2011 Quantitative measurements
Tracking
Zebrafish Immunology
Physiology
Volocity
UltraVIEW
Human Cytomegalovirus-induced cytoplasmic remodelling: a 3D perspective Subhendu Das and Philip E. Pellett Journal of Virology; 85 (12): 5864–5879 June 2011 Colocalization
Quantitative measurements
Visualization
Human Virology Volocity
In vivo imaging of the effects of dexamethasone on the host response to biomaterials Dang TT, Bratlie KM, Bogatyrev SR, Chen XY, Langer R and Anderson DG Biomaterials; 32 (19): 4464-4470 July 2011 Mouse Immunology
Pharmacology
ProSense
In vivo fluorescent imaging: a novel technique for analyzing biocompatibility Bratlie KM, Dang TT, Lyle S, Nahrendorf M, Weissleder R, Langer R and Anderson DG PLoS ONE 5 (4): e10032. doi:10.1371/journal.pone.0010032 Apr 2010 Mouse Immunology
Method Development
ProSense
Identification and characterization of novel histone variants: FRAP studies using the UltraVIEW VoX Sonja M. Wiedemann, Silke N. Mildner, Clemens Bönisch, Lars Israel, Andreas Maiser, Sarah Matheisl, Tobias Straub, Rainer Merkl, Heinrich Leonhardt, Elisabeth Kremmer, Lothar Schermelleh and Sandra B. Hake Journal of Cell Biology; 190 (5): 777-791 Sep 2010 FRAP Human Genetics
Cell Biology
UltraVIEW
Investigating human respiratory viral infections using Volocity Marchant D, Singhera GK, Utokaparch S, Hackett TL, Boyd JH, Luo Z, Si X, Dorscheid DR, McManus BM and Hegele RG Journal of Virology; 84 (21): 11359-11373 Nov 2010 Colocalization
Quantitative measurements
Human Infectious Diseases
Virology
Volocity
Investigating the effect of HIV-1 infection on cytoskeleton dynamics Cinzia Nobile, Dominika Rudnicka, Milena Hasan, Nathalie Aulner, Francoise Porrot, Christophe Machu, Olivier Renaud, Marie-Christine Prevost, Claire Hivroz, Olivier Schwartz and Nathalie Sol-Foulon Journal of Virology; 84(5): 2282 – 2293 Mar 2010 Acquisition
Quantitative measurements
Visualization
Human Infectious Diseases
Virology
Acapella
Opera
UltraVIEW
Colocalization studies reveal a novel interaction between the tumor suppressor protein Par4 and NFκB in human colon cancer cells Bi-Dar Wang, Christina Leah B Kline, Danielle M Pastor, Thomas L Olson, Bryan Frank, Truong Luu, Arun K Sharma, Gavin Robertson, Matthew T Weirauch, Steven R Patierno, Joshua M Stuart, Rosalyn B Irby and Norman H Lee Molecular Cancer; 9: 98 Apr 2010 Colocalization Human Cancer Biology Volocity
UltraVIEW VoX FRAP studies offer new insights into endocytosis Wu M, Huang B, Graham M, Raimondi A, Heuser JE, Zhuang X and De Camilli P Nature Cell Biology; 12 (9): 902 -908. FRAP Molecular Biology
Cell Biology
Volocity
UltraVIEW
Visualizing Chromatin Dynamics in Cycling Cells using the UltraVIEW VoX Hilmar Strickfaden, Andreas Zunhammer, Silvana van Koningsbruggen, Daniela Köhler and Thomas Cremer Nucleus; 1 (3): 1-15 May/June 2010 Acquisition
FRAP
Human Cell Cycle
Genetics
UltraVIEW
Cranial Motor Neuron and Oligodendrocyte Development Denise A. Zannino and Bruce Appel The Journal of Neuroscience; 29 (8): 2322-2333 Feb 2009 Acquisition
Visualization
Zebrafish Developmental Biology
Neuroscience
Volocity
UltraVIEW
A key role for polarity signalling in breast cancer metastasis Alicia M. Viloria-Petit, Laurent David, Jun Yong Jia, Tuba Erdemir, Anita L. Baneb, Dushanthi Pinnaduwage, Luba Roncari, Masahiro Narimatsu, Rohit Bose, Jason Moffat, John W. Wong, Robert S. Kerbel, Frances P. O'Malley, Irene L. Andrulis, Jeffrey L. Wrana PNAS; 106 (33): 14028-14033 Aug 2009 Quantitative measurements
Visualization
Human,Mouse Cancer Biology TSA
Volocity
Three-dimensional rendering of adeno-associated viral infection Johnson J S and Samulski R J J. Virol; 83: 2632 - 2644 Mar 2009 Visualization Human Virology Volocity
Live cell imaging of Drosophila S2 anaphase cells using the UltraVIEW VoX Hideki Yokoyama, Sofia Rybina, Rachel Santarella-Mellwig, Iain W. Mattaj and Eric Karsenti J. Cell Biol.; 187: 813 - 829 Dec 2009 Acquisition Drosophila Cell Cycle UltraVIEW
Endothelial myosin in tumor invasion: a three-dimensional FRET study Satya Khuon, Luke Liang, Robert W. Dettman, Peter H. S. Sporn, Robert B. Wysolmerski and Teng-Leong Chew Journal of Cell Science; 123: 431 - 440 Nov 2009 FRET
Ratio Imaging
Visualization
Mouse Cancer Biology Volocity
Studying GPCR Trafficking Using High Content Screening (HCS) YingJie Zhu, Michele Agler, Andrew Alt, Jonathan O’Connell, Martyn Banks and Jenny Xie International Drug Discovery 5 (2): 10-16. April 2010 Acquisition
Quantitative measurements
Visualization
Hamster (CHO) Cell Signalling
Drug Discovery
Acapella
Opera
Sym004: A Novel Anti-EGFR Antibody Mixture with Superior Anticancer Efficacy Mikkel Wandahl Pedersen, Helle Jane Jacobsen, Klaus Koefoed, Adam Hey, Charles Pyke, John Sørensen Haurum and Michael Kragh Cancer Res.; 70 (2) 588 - 597 Jan 2010 Quantitative measurements Human Cancer Biology Acapella
Opera
Oligodendrocyte precursors generate myelinating oligodendrocytes and piriform projection neurons in adult mice Rivers LE, Young KM, Rizzi M, Jamen F, Psachoulia K, Wade A, Kessaris N and Richardson WD Nature Neuroscience; 11: 1392-1401 Oct 2008 Visualization Mouse Neuroscience Volocity
UltraVIEW
Live cell imaging of single stem cells within their niche Fichelson P, Moch C, Ivanovitch K, Martin C, Sidor CM, Lepesant J-A, Bellaiche Y and Huynh J-R Nature Cell Biology; 11 (6) 685 - 693 Jun 2009 Acquisition
Quantitative measurements
Visualization
Drosophila Stem Cell Research Volocity
UltraVIEW
A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases Cindy M. Quezada, Stuart W. Hicks, Jorge E. Galán and C. Erec Stebbins (2009) PNAS; 106: 4864 - 4869 Mar 2009 Acquisition
Visualization
Salmonella Infectious Diseases
Protein Biochemistry
Volocity
Multipotent progenitor/stem cells in the adult pituitary gland Fauquier T, Rizzoti K, Dattani M, Lovell-Badge R and Robinson I C A F PNAS; 105 (8): 2907-2912 Feb 2008 Visualization Mouse Stem Cell Research Volocity
Studies of the prodrug AQ4N in patients with advanced solid tumors Albertella MR, Loadman PM, Jones PH, Phillips RM, Rampling R, Burnet N, Alcock C, Anthoney A, Vjaters E, Dunk CR, Harris PA, Wong A, Lalani AS and Twelves CJ Clin. Cancer Res; 14: 1096-1104 Feb 2008 Visualization Human Cancer Biology Volocity
The role of Slb/Wnt11 at the onset of zebrafish gastrulation Ulrich F, Concha ML, Heid PJ, Voss E, Witzel S, Roehl H, Tada M, Wilson SW, Adams RJ, Soll DR and Heisenberg CP Development; 130 (22): 5375 - 5384 Nov 2003 Quantitative measurements
Visualization
Zebrafish Developmental Biology Volocity
Visualizing the dynamics of cAMP formation in neurons using FRET Neves SR, Tsokas P, Sarkar A, Grace EA, Rangamani P, Taubenfeld SM, Alberini CM, Schaff JC, Blitzer RD, Moraru II and Iyengar R Cell. 133 (4): 666-680 May 2008 FRET
Quantitative measurements
Rat Neuroscience Volocity
Nanoscale Increases in CD2-CD48-mediated Intermembrane Spacing Decrease Adhesion and Reorganize the Immunological Synapse Milstein O, Tseng S-Y, Starr T, Llodra J, Nans A, Liu M, Wild MK, van der Merwe PA, Stokes DL, Reisner Y and Dustin ML J. Biol. Chem.; 283 (49): 34414-34422 Dec 2008 Quantitative measurements
Visualization
Hamster (CHO) Immunology Volocity
Sorting nexin-1 defines an early phase of Salmonella-containing vacuole remodelling during Salmonella Typhimurium infection Bujny M V, Ewels P A, Humphrey S, Attar N, Jepson M A and Cullen P J Journal of Cell Science; 121 (12): 2027-2036 May 2008 Deconvolution
Visualization
Salmonella Infectious Diseases Volocity
Transepithelial Projections from Basal Cells are Luminal Sensors in Pseudostratified Epithelia Winnie Wai Chi Shum, Nicolas Da Silva, Mary McKee, Peter J.S. Smith, Dennis Brown and Sylvie Breton Cell; 135 (6): 1108 - 1117 Dec 2008 Visualization Rat Cell Biology Volocity
Measurement of tumor volume using Volocity Estrada CR, Salanga M, Bielenberg DR, Harrell WB, Zurakowski D, Zhu X, Palmer MR, Freeman MR and Adam RM Cancer Res. 66: 3078-3086 Mar 2006 Quantitative measurements
Visualization
Rat Cancer Biology Volocity
Analysis of box jellyfish photosytems using 64-bit Volocity Ekstrom P, Garm A, Palsson J, Vihtelic T S and Nilsson D-E Cell and Tissue Research; 333 (1): 115 – 124 May 2008 Visualization Jellyfish Sensory Biology Volocity
Golgi Cell Dendrites are Restricted by Purkinje Cell Stripe Boundaries in the Adult Mouse Cerebellar Cortex Roy V. Sillitoe, Seung-Hyuk Chung, Jean-Marc Fritschy, Monica Hoy and Richard Hawkes J. Neurosci.; 28: 2820-2826 Mar 2008 Acquisition
Deconvolution
Visualization
Mouse Neuroscience Volocity
CD45-Positive Blood Cells Give Rise to Uterine Epithelial Cells in Mice Bratincsak A, Brownsteina MJ, Cassiani-Ingoni R, Pastorino S, Szalayova I, Toth ZE, Key S, Németh K, Pickela J and Mezeye E Stem Cells; 25 (11): 2820 -2826 Nov 2007 Deconvolution
Visualization
Mouse Stem Cell Research Volocity
A class one ADP-ribosylation GTPase – activating protein is for maintaining directional root hair growth in Arabidopsis thaliana Cheol-Min Y, Jiangqi W, Motes CM, Sparks JA and Blancaflor EB Plant Phys.; 147: 1659-1674 Jun 2008 Quantitative measurements
Tracking
Arabidopsis thaliana Plant Biology Volocity
UltraVIEW
Organization of &beta:-adrenoceptor signaling compartments by sympathetic innervation of cardiac myocytes Shcherbakova O G, Hurt CM, Xiang Y, Dell'Acqua ML, Zhang Q, Tsien RW and Kobilka BK J. Cell Biol.; 176 (4): 521-533 Feb 2007 Visualization Mouse Cardiovascular Research Volocity
Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesis Torkko JM, Manninen A, Schuck S and Simons K J. Cell Science; 121: 1193-1203 Mar 2008 RNAi
Visualization
Dog (MDCK) Cell Biology Volocity
In Vivo Role of Dendritic Cells in a Murine Model of Pulmonary Cryptococcosis Wozniak KL, Vyas JM and Levitz SM Infection and Immunity; 74 (7): 3817-3824 Jul 2006 Acquisition Micro-organism Infectious Diseases UltraVIEW
Genetic and spectrally distinct in vivo imaging: embryonic stem cells and mice with widespread expression of a monomeric red fluorescent protein Long JZ, Lackan CS and Hadjantonakis AK BMC Biotechnol; 5:20 Jul 2005 Visualization Mouse Developmental Biology Volocity
Identification of a putative nuclear localization sequence within ANG II AT1A receptor associated with nuclear transport Morinelli TA, Raymond JR, Baldys A, Yang Q, Lee MH, Luttrell L and Ullian ME American Journal of Cell Physiology; 292 (4): C1398-408 Apr 2007 Visualization Human Cell Signalling Volocity
A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress Nombela-Arrieta C, Mempel TR, Soriano SF, Mazo I, Wymann MP, Hirsch E, Martínez-A C, Fukui Y, von Andrian UH and Stein JV J Exp Med; 204 (3): 497-510 Mar 2007 Tracking
Visualization
Mouse Immunology Volocity
Vesicular Glutamate Transporter 2 Is Required for Central Respiratory Rhythm Generation But Not for Locomotor Central Pattern Generation Wallén-Mackenzie A, Gezelius H, Thoby-Brisson M, Nygård A, Enjin A, Fujiyama F, Fortin G and Kullander K J. Neuroscience; 26 (47): 12294-12307 Nov 2006 Acquisition
Visualization
Mouse Neuroscience Volocity
Donut-Like Topology of Synaptic Vesicles with a Central Cluster of Mitochondria Wrapped into Membrane Protrusions: A Novel Structure-Function Module of the Adult Calyx of Held Wimmer VC, Horstmann H, Groh A and Kuner T J. Neuroscience; 26 (1): 109-116 Jan 2006 Quantitative measurements
Visualization
Rat Neuroscience Volocity
Photoswitching and Vesicle Tracking Applications using the UltraVIEW PhotoKinesis accessory Dr Patrick Courtney and colleagues (PerkinElmer, UK) in collaboration with Professor Pete Cullen and colleagues (University of Bristol) Research note Tracking Human Protein Biochemistry
Cell Biology
UltraVIEW
Axodendritic Contacts onto Calcium/Calmodulin-Dependent Protein Kinase Type II-Expressing Neurons in the Barn Owl Auditory Space Map Rodriguez-Contreras A, Liu XB and DeBello WM J. Neuroscience; 25 (23): 5611-5622 Jun 2005 Deconvolution
Quantitative measurements
Visualization
Neuroscience
Sensory Biology
Volocity
Dynamics of the basement membrane in invasive epithelial clusters in Drosophila Medioni C and Noselli S Development; 132: 3069-3077 Apr 2005 Visualization Drosophila Developmental Biology Volocity
Three-Dimensional In Vivo Imaging of the Mouse Intraocular Vasculature during Development and Disease Ritter MR, Aguilar E, Banin E, Scheppke L, Uusitalo-Jarvinen H and Friedlander M Investigative Ophthalmology & Visual Science; 46 (9); 3021-3026 Sep 2005 Visualization Mouse Cardiovascular Research Volocity
Listeria monocytogenes Invades the Epithelial Junctions at Sites of Cell Extrusion Pentecost M, Otto G, Theriot JA, Amieva MR PLOS Pathogens; 2: 29-40 Jan 2006 Visualization Listeria monocytogenes Infectious Diseases Volocity
Actin and agonist MHC–peptide complex–dependent T cell receptor microclusters as scaffolds for signaling Campi G, Varma R and Dustin ML Journal. Exp. Med.; 202 (8): 1031-1036 Oct 2005 Colocalization
Quantitative measurements
Visualization
Mouse Immunology Volocity
Influence on neural lineage and mode of division in zebrafish retina in vivo Poggi L, Vitorino M, Masai I and Harris WA J. Cell Biology; 171 (6): 991-999 Dec 2005 Tracking
Visualization
Zebrafish Developmental Biology Volocity
Mitochondrial motility in budding yeast Fehrenbacher KL, Boldogh IR and Pon LA Molecular Biology of the Cell; 16 (11): 5094-5102 Nov 2005 Deconvolution
Visualization
Yeast Organelle Biology Openlab
Volocity
ImmunoFISH analysis in Drosophilia Eye Disc Dr Emilie Brasset and colleagues Research note Quantitative measurements
Visualization
Drosophila Genetics Volocity
Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells Bagnoli F, Buti L, Tompkins L, Covacci A and Amieva MR PNAS; 102 (45): 16339-16344 Nov 2005 Quantitative measurements
Visualization
Dog (MDCK) Infectious Diseases Volocity
The cohesion protein ORD is required for homologue bias during meiotic recombination Webber HA, Howard L and Bickel SE The Journal of Cell Biology; 164 (6): 819-829 Mar 2004 Acquisition
Deconvolution
Visualization
Drosophila Cell Cycle Openlab
Volocity
Coupling of ER exit to microtubules through direct interaction of COPII with dynactin Watson P, Forster R, Palmer KJ, Pepperkok R and Stephens DJ Nature Cell Biology; 7 (1): 48-55 Jan 2005 Quantitative measurements
Visualization
Human Organelle Biology Volocity
Mammalian Pins Is a Conformational Switch that Links NuMA to Heterotrimeric G Proteins Du Q and Macara IG Cell; 119 (4): 503-516 Nov 2004 FRET Dog (MDCK) Cell Cycle Openlab
Active cell migration drives the unilateral movements of the anterior visceral endoderm Srinivas S, Rodriguez T, Clements M, Smith JC and Beddington RSP Development; 131: 1157-1164 Feb 2004 Quantitative measurements
Tracking
Visualization
Mouse Developmental Biology Volocity
Dishevelled (Dvl-2) activates canonical Wnt signaling in the absence of cytoplasmic puncta Smalley MJ, Signoret N, Robertson D, Tilley A, Hann A, Ewan K, Ding Y, Paterson H and Dale TC J. Cell Science; 118: 5279-5289 Nov 2005 Acquisition
Quantitative measurements
Visualization
Dog (MDCK),Human Cell Signalling
Developmental Biology
Volocity
Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo Shakhar G, Lindquist RL, Skokos D, Dudziak D, Huang JH, Nussenzweig MC, Dustin ML Nature Immunology; 6 (7): 707-714 Jul 2005 Quantitative measurements
Tracking
Visualization
Mouse Immunology Volocity
Golgi body movement in the plant-cell secretory pathway Runions J and Hawes C Research note Deconvolution
Quantitative measurements
Visualization
Arabidopsis thaliana Organelle Biology
Plant Biology
Volocity
Molecular Dynamics of Aurora-A Kinase in Living Mitotic Cells Simultaneously Visualized with Histone H3 and Nuclear Membrane Protein Importinα Sugimoto K, Urano T, Zushi H, Inoue K, Tasaka H, Tachibana M and Dotsu M Cell Structure and Function; 27: 457-467 Feb 2002 Visualization Human Cell Cycle Volocity
3D morphology of tumour cells Vial E Research note Quantitative measurements
Visualization
Human Cancer Biology Volocity
T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases Mempel TR, Henrickson SE and von Andrian UH Nature; 427: 154 - 159 Jan 2004 Quantitative measurements
Visualization
Mouse Immunology Volocity
Control of cell division in yeast Hyams J Research note Acquisition
Visualization
Yeast Cell Cycle Openlab
Dynamics of varicosities in the CNS Condron B Research note Visualization Drosophila Developmental Biology
Neuroscience
Volocity
Subcellular calcium signals in T-lymphocytes Guse A Research note Acquisition
Deconvolution
Visualization
Cell Signalling Openlab
Golgi biogenesis in Toxoplasma gondii Pelletier L, Stern CA, Pypaert M, Sheff D, Ngô HM, Roper N, He CY, Hu K, Toomre D, Coppens I, Roos DS, Joiner KA and Warren G Nature; 418: 548-552 Aug 2002 Visualization Toxoplasmi Gondii Organelle Biology Volocity
The C.elegans MAPK phosphatase LIP-1 is required for the G2/M meiotic arrest of developing oocytes Hajnal A and Berset T EMBO; 21: 4317-4326 Jun 2002 Visualization Caenorhabditis elegans Cell Signalling
Developmental Biology
Volocity
A common mechanism of action for three mood-stabilizing drugs Williams RSB, Cheng L, Mudge AW and Harwood AJ Nature; 417: 292-295 May 2002 Acquisition
Visualization
Dictyostelium,Rat Toxicology Openlab
Salmonella uptake studies Koronakis V Research note Visualization Human,Salmonella Infectious Diseases Volocity
Cytokinesis in C. elegans Skop A Research note Acquisition
Visualization
Caenorhabditis elegans Cell Cycle Openlab
Arrested Oligodendrocyte Lineage Progression During Human Cerebral White Matter Development: Dissociation Between the Timing of Progenitor Differentiation and Myelinogenesis Back SA, Luo NL, Borenstein NS; Volpe JJ and Kinney HC Journal of Neuropathology & Experimental Neurology; 61 (2): 197-211 Feb 2002 Visualization Human Developmental Biology
Neuroscience
Volocity
Calcium signaling in CHO cells Hill S and Briddon S Research note Acquisition
Ratio Imaging
Visualization
Hamster (CHO) Cell Signalling Openlab
Neuromuscular junction studies Bewick G Research note Visualization Rat Neuroscience Volocity
Colonic mucosal studies Pedley K and Naftalin R Research note Quantitative measurements Rat Cell Signalling Volocity